The type Ic morphology of urinary calculi: an alert to primary hyperoxaluria? Experience with 43 Moroccan children

Primary hyperoxaluria is the most severe stone disease responsible for multiple recurrence and impairment of kidney function. It a rare inherited with an autosomal transmission. Due to high proportion consanguineous marriages by comparison other areas in world, this pathology more frequent North Africa. Stones are made calcium oxalate monohydrate, which not unique cannot help physicians diagnosis. By contrast, morphology may be useful marker pathology. We report our experience based on 614 stones from Moroccan children analyzed infrared spectroscopy examined stereomicroscopy determination their morphological type. Our results show that 85 (13.8%) exhibit type Ic morphology, strongly suggestive patients. was confirmed all subjects subgroup 43 patients who benefited urinary biochemical explorations revealing whewellite crystalluria very creatinine ratio.